2320521-34-2
2320521-34-2
Chemical Structure
ARN19689
- CAS No.: 2320521-34-2
- Formula:C19H27N5O4S
- Molecular Weight:421.51
IUPAC Name: (1R,3r,5S)-8-((3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl)-3-((5-(ethoxymethyl)pyrazin-2-yl)oxy)-8-azabicyclo[3.2.1]octane
InChIKey: FVIHLKFGYOKIDE-FVQHAEBGSA-N
SMILES: O=S(N1[C@@H]2C[C@H](C[C@H]1CC2)OC3=NC=C(COCC)N=C3)(C4=C(C)NN=C4C)=O
Biological Activity: ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions[1].
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ARN19689 | ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions. | |||||||||||||||||||||
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