23255-54-1
23255-54-1
Chemical Structure
Dihydro-β-erythroidine
- CAS No.: 23255-54-1
- Formula:C16H21NO3
- Molecular Weight:275.34
IUPAC Name: (2S,13bS)-2-methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-pyrano[4',3':3,4]pyrido[2,1-i]indol-12-one
InChIKey: ALSKYCOJJPXPFS-BBRMVZONSA-N
SMILES: CO[C@H]1CC=C2CCN3CCC4=C([C@@]32C1)CC(OC4)=O
Biological Activity: Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2].
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Dihydro-β-erythroidine | Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced. | |||||||||||||||||||||
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References
- [1]. Shoaib M, et al. Antagonism of stimulus properties of nicotine by dihydro-beta-erythroidine (DHbetaE) in rats. Psychopharmacology (Berl). 2000 Apr;149(2):140-6. [Content Brief]
- [2]. Cheeta S, et al. Antagonism of the anxiolytic effect of nicotine in the dorsal raphe nucleus by dihydro-beta-erythroidine. Pharmacol Biochem Behav. 2001 Dec;70(4):491-6. [Content Brief]
