23350-58-5
23350-58-5
Chemical Structure
Crotonamide
- CAS No.: 23350-58-5
- Formula:C4H7NO
- Molecular Weight:85.10
IUPAC Name: (E)-but-2-enamide
InChIKey: NQQRXZOPZBKCNF-NSCUHMNNSA-N
SMILES: C/C=C/C(N)=O
Biological Activity: Crotonamide is a drug intermediate that can be used for the synthesis of EGFR inhibitors[1].
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Crotonamide | Crotonamide is a drug intermediate that can be used for the synthesis of EGFR inhibitors. | |||||||||||||||||||||
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References
- [1]. Wissner A, et al. Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor-2 (HER-2). J Med Chem. 2003 Jan 2;46(1):49-63. [Content Brief]
