2337386-47-5
Chemical Structure
PARP/PI3K-IN-1
- CAS No.: 2337386-47-5
- Formula:C33H28F4N8O3
- Molecular Weight:660.62
IUPAC Name: 4-(3-(2-(6-amino-4-(trifluoromethyl)pyridin-3-yl)-4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
InChIKey: LIQDGVXNWJAUNO-UHFFFAOYSA-N
SMILES: O=C1NN=C(CC2=CC=C(F)C(C(N3CCC4=C(N5CCOCC5)N=C(C6=C(C(F)(F)F)C=C(N)N=C6)N=C4C3)=O)=C2)C7=C1C=CC=C7
Biological Activity: PARP/PI3K-IN-1 (compound 15) is a potent PARP/PI3K inhibitor with pIC50 values of 8.22, 8.44, 8.25, 6.54, 8.13, 6.08 for PARP-1, PARP-2, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively. PARP/PI3K-IN-1 is a highly effective anticancer compound targeted against a wide range of oncologic diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PARP/PI3K-IN-1 | 99.40% | PARP/PI3K-IN-1 (compound 15) is a potent PARP/PI3K inhibitor with pIC50 values of 8.22, 8.44, 8.25, 6.54, 8.13, 6.08 for PARP-1, PARP-2, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively. PARP/PI3K-IN-1 is a highly effective anticancer compound targeted against a wide range of oncologic diseases. | ||||||||||||||||||||
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