2341796-79-8
2341796-79-8
Chemical Structure
(S,R,S)-AHPC-C8-NH2
Synonym(s): VH032-C8-NH2
- CAS No.: 2341796-79-8
- Formula:C31H47N5O4S
- Molecular Weight:585.80
IUPAC Name: (2S,4R)-1-((S)-2-(9-aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: QLJZVMJBYNFUSG-CERRFVOPSA-N
SMILES: O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCCCN)=O
Biological Activity: (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].
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(S,R,S)-AHPC-C8-NH2 | 97.04% | (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1. | ||||||||||||||||||||
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(S,R,S)-AHPC-C10-NH2 | (S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC. | |||||||||||||||||||||
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(S,R,S)-AHPC-C8-NH2 dihydrochloride | (S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1. | |||||||||||||||||||||
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(S,R,S)-AHPC-C8-NH2 hydrochloride | (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | |||||||||||||||||||||
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(S,R,S)-AHPC-C7-amine | (S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. | |||||||||||||||||||||
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(S,R,S)-AHPC-C7-amine dihydrochloride | (S,R,S)-AHPC-C7-amine dihydrochloride is the dihydrochloride form of (S,R,S)-AHPC-C7-amine (HY-136186). (S,R,S)-AHPC-C7-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker. (S,R,S)-AHPC-C7-amine can be used for estrogen-related receptor α (ERRα) PROTAC degrader. | |||||||||||||||||||||
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(S,R,S)-AHPC-C7-amine hydrochloride | (S,R,S)-AHPC-C7-amine (VH032-C7-amine) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. | |||||||||||||||||||||
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(S,R,S)-AHPC-CO-C9-NH2 | (S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs. | |||||||||||||||||||||
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(S,R,S)-AHPC-CO-C9-NH2 hydrochloride | (S,R,S)-AHPC-CO-C9-NH2 (hydrochloride) is a von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs.. | |||||||||||||||||||||
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VH 032 amide-alkylC9-amine hydrochloride | 98.01% | VH 032 amide-alkylC9-amine hydrochloride (Linker 33) is TRK ligand conjugated to the degradation tag. | ||||||||||||||||||||
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(S,R,R)-VH032-CO-C8-NH2 | (S,R,R)-VH032-CO-C8-NH2 (Compound 9) is a conjugate of an E3 ligase ligand and a linker, which can be used for the synthesis of PROTACs, such as UNC9036 (HY-158048). | |||||||||||||||||||||
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