2353522-15-1
2353522-15-1
Chemical Structure
Paltimatrectinib
Synonym(s): PBI-200; PPI-5278
- CAS No.: 2353522-15-1
- Formula:C20H15F5N6
- Molecular Weight:434.37
IUPAC Name: (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-(4-(trifluoromethyl)-1H-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine
InChIKey: FYPXPQSPRRZJCK-MRXNPFEDSA-N
SMILES: FC(F)(C1=CN(N=C1)C2=C3N(C=CC(N4[C@](C5=C(C=CC(F)=C5)F)([H])CCC4)=N3)N=C2)F
Biological Activity: Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Paltimatrectinib | 99.95% | Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases. | ||||||||||||||||||||
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