2357123-44-3
2357123-44-3
Chemical Structure
TBZ-1
- CAS No.: 2357123-44-3
- Formula:C68H90N14O15S
- Molecular Weight:1375.59
InChIKey: NCYIXCUWFNKWEW-OVLROGABSA-N
SMILES: O=C(O1)C2=C(C=CC=C2)C31C4=CC=C(NC([C@H](CC5=CNC6=CC=CC=C65)NC([C@H](CCSC)NC([C@H]([C@H](O)C)NC([C@@H](N)C)=O)=O)=O)=O)C=C4OC7=C3C=CC(NC(CCC(NCC(N(CCCN(C)C)CC(N(CCCO)CC(N(CCCN(C)C)CC(N)=O)=O)=O)=O)=O)=O)=C7
Biological Activity: TBZ-1 is a fluorescent probe that monitors the activity of immunoproteasome (Proteasome) (iCP) in cells. TBZ-1 undergoes fluorescence activation after being selectively cleaved by β5i, which is used for intracellular activity monitoring. TBZ-1 is applicable to cancer-related research[1][2].
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TBZ-1 | TBZ-1 is a fluorescent probe that monitors the activity of immunoproteasome (Proteasome) (iCP) in cells. TBZ-1 undergoes fluorescence activation after being selectively cleaved by β5i, which is used for intracellular activity monitoring. TBZ-1 is applicable to cancer-related research. | |||||||||||||||||||||
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