2357123-49-8
2357123-49-8
Chemical Structure
Ac-ANW-AMC
- CAS No.: 2357123-49-8
- Formula:C30H32N6O7
- Molecular Weight:588.61
IUPAC Name: (S)-N-((6R,9S,12S,15S,21S)-12-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-1-imino-15-isobutyl-9,23-dimethyl-8,11,14,17,20-pentaoxo-2,7,10,13,16,19-hexaazatetracosan-21-yl)-1-(2,4-dinitrophenyl)pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
InChIKey: LMUIALVDZMMUMF-ZCWWJEROSA-N
SMILES: O=C1OC2=CC=C(C=C2C(C)=C1)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C)NC(C)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O
Biological Activity: Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ac-ANW-AMC | 98.88% | Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm). | ||||||||||||||||||||
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References
- [1]. Winter, M.B., La Greca, F., Arastu-Kapur, S., et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. eLife 6:e27364, (2017).
- [2]. Sumin Kim, et al. Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates. Immune Netw. 2022 Apr 15;22(3):e28. [Content Brief]
