2360528-45-4
Chemical Structure
PROTAC IRAK4 degrader-4
- CAS No.: 2360528-45-4
- Formula:C41H38F3N11O10
- Molecular Weight:901.80
IUPAC Name: N-(3-carbamoyl-1-(4-((2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)carbamoyl)phenyl)-1H-pyrazol-4-yl)-2-(2-((2,2,2-trifluoroethyl)amino)pyridin-4-yl)oxazole-4-carboxamide
InChIKey: LFOAFZGTRKLOHG-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2=CC=C(C(NCCOCCOCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N
Biological Activity: PROTAC IRAK4 degrader-4 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127[1].
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PROTAC IRAK4 degrader-4 | PROTAC IRAK4 degrader-4 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127. | |||||||||||||||||||||
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