2361192-21-2
2361192-21-2
Chemical Structure
BTK-IN-9
- CAS No.: 2361192-21-2
- Formula:C25H19N7O4
- Molecular Weight:481.46
IUPAC Name: 2-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-N-(4-nitrophenyl)acetamide
InChIKey: VLPWPOWMTKZZQI-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C([N+]([O-])=O)C=C1)CN2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52
Biological Activity: BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells[1].
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BTK-IN-9 | BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells. | |||||||||||||||||||||
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