23627-87-4
23627-87-4
Chemical Structure
Kaempferol 3-O-β-D-galactopyranoside
Synonym(s): Trifolin
- CAS No.: 23627-87-4
- Formula:C21H20O11
- Molecular Weight:448.38
IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: JPUKWEQWGBDDQB-DTGCRPNFSA-N
SMILES: O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C=C3)=C1O[C@@H]4O[C@@H]([C@H](O)[C@H](O)[C@H]4O)CO
Biological Activity: Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kaempferol 3-O-β-D-galactopyranoside | 99.58% | Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects. | ||||||||||||||||||||
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Astragalin (Standard) | 98.13% | Astragalin (Standard) is the analytical standard of Astragalin. This product is intended for research and analytical applications. Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis. | ||||||||||||||||||||
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Hyperoside | 99.71% | Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis. | ||||||||||||||||||||
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Rhamnocitrin 3-glucoside | Rhamnocitrin 3-glucoside (Rhamnocitrin-3-O-β-D-glucopyranoside) is a natural product that can be isolated from Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (AM). | |||||||||||||||||||||
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Afzelin | 99.62% | Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin. | ||||||||||||||||||||
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Isoquercitrin | 99.64% | Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies. | ||||||||||||||||||||
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Galanginin | Galanginin is a natural flavonoid. | |||||||||||||||||||||
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Kaempferol-3-O-β-D-6''-acetylglucoside | 98.98% | Kaempferol-3-O-β-D-6 "-acetylglucoside is a flavonoid glycoside compound that can be isolated from Arnica. | ||||||||||||||||||||
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Juglanin | 99.76% | Juglanin, a occurring flavonoid that can be isolated from crude Polygonum aviculare, is a JNK acticator, with anti-inflammatory, anti-oxidant and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells. | ||||||||||||||||||||
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Kaempferol 3-O-β-D-glucuronide (Standard) | ≥98% | Kaempferol 3-O-β-D-glucuronide (Standard) (Kaempferol-3-glucuronide (Standard)) is the analytical standard of Kaempferol 3-O-β-D-glucuronide (HY-N7176). This product is intended for research and analytical applications. Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism. | ||||||||||||||||||||
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6-Hydroxykaempferol 3-O-β-D-glucoside | 99.94% | 6-Hydroxykaempferol 3-O-β-D-glucoside possesses anticancer activity and induces apoptosis. | ||||||||||||||||||||
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References
- [1]. da Silva I, et al. Structure determination of monohydrated trifolin (kaempferol 3-O-β-D-galactopyranoside) from laboratory powder diffraction data. J Pharm Sci. 2011;100(4):1588-1593. [Content Brief]
- [2]. Kim MJ, et al. Trifolin induces apoptosis via extrinsic and intrinsic pathways in the NCI-H460 human non-small cell lung-cancer cell line. Phytomedicine. 2016 Sep 15;23(10):998-1004. [Content Brief]
- [3]. Zhang F, et al. Trifolin Attenuates Hypertension-Mediated Cardiac Injury by Inhibiting Cardiomyocyte Apoptosis: Mechanistic Insights and Therapeutic Potential. Eur J Pharmacol. 2024 Nov 9:177125. [Content Brief]
