2373280-36-3
2373280-36-3
Chemical Structure
HDL-16
- CAS No.: 2373280-36-3
- Formula:C14H11BrN2O
- Molecular Weight:303.15
InChIKey: JSSZKVFZNCWYID-UHFFFAOYSA-N
SMILES: BrC(C=C1)=CC=C1NCC2=NC3=CC=CC=C3O2
Biological Activity: HDL-16 is a potent P2Y14R antagonist with an IC50 of 0.3095 nM. HDL-16 ameliorates DSS (HY-116282C)-induced colitis through suppressing necroptosis of intestinal epithelium cells (IECs) and protecting mucosal barrier function[1].
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HDL-16 | 99.19% | HDL-16 is a potent P2Y14R antagonist with an IC50 of 0.3095 nM. HDL-16 ameliorates DSS (HY-116282C)-induced colitis through suppressing necroptosis of intestinal epithelium cells (IECs) and protecting mucosal barrier function. | ||||||||||||||||||||
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