2375780-95-1
2375780-95-1
Chemical Structure
DENV-IN-6
- CAS No.: 2375780-95-1
- Formula:C23H26ClFN4OS
- Molecular Weight:461.00
IUPAC Name: 2-(((4-chloro-5-(4-fluorophenyl)-1H-pyrazol-3-yl)methyl)thio)-6-(cyclohexylmethyl)-5-ethylpyrimidin-4(3H)-one
InChIKey: BEOGBSUQIKKYRA-UHFFFAOYSA-N
SMILES: CCC1=C(N=C(NC1=O)SCC2=NNC(C3=CC=C(C=C3)F)=C2Cl)CC4CCCCC4
Biological Activity: DENV-IN-6 is a potent DENV (I-IV) inhibitor with EC50s of 17.5, 13.20, 6.8 and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. DENV-IN-6 also exhibits activity of anti-HIV-1IIIB (EC50=0.0181 µM; CC50=64.92 µM)[1].
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DENV-IN-6 | DENV-IN-6 is a potent DENV (I-IV) inhibitor with EC50s of 17.5, 13.20, 6.8 and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. DENV-IN-6 also exhibits activity of anti-HIV-1IIIB (EC50=0.0181 µM; CC50=64.92 µM). | |||||||||||||||||||||
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