2375781-06-7
2375781-06-7
Chemical Structure
DENV-IN-5
- CAS No.: 2375781-06-7
- Formula:C23H25ClF2N4OS
- Molecular Weight:478.99
IUPAC Name: 2-(((4-chloro-5-(3,4-difluorophenyl)-1H-pyrazol-3-yl)methyl)thio)-6-(cyclohexylmethyl)-5-ethylpyrimidin-4(3H)-one
InChIKey: GYGFJKYRVOOELP-UHFFFAOYSA-N
SMILES: CCC1=C(N=C(NC1=O)SCC2=NNC(C3=CC(F)=C(C=C3)F)=C2Cl)CC4CCCCC4
Biological Activity: DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].
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DENV-IN-5 | DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM. | |||||||||||||||||||||
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