2377849-57-3
2377849-57-3
Chemical Structure
E3 ligase Ligand 22
- CAS No.: 2377849-57-3
- Formula:C28H34N6O4
- Molecular Weight:518.61
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-(((1-(1-((1-methylcyclobutyl)methyl)piperidin-4-yl)-1H-pyrazol-4-yl)methyl)amino)isoindoline-1,3-dione
InChIKey: VEXNVDNDFCERDC-UHFFFAOYSA-N
SMILES: CC1(CCC1)CN2CCC(CC2)N3C=C(C=N3)CNC4=C5C(N(C(C5=CC=C4)=O)C6CCC(NC6=O)=O)=O
Biological Activity: E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1].
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E3 ligase Ligand 22 | E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway. | |||||||||||||||||||||
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