2378582-97-7
2378582-97-7
Chemical Structure
Thalidomide-SH
- CAS No.: 2378582-97-7
- Formula:C13H10N2O4S
- Molecular Weight:290.29
IUPAC Name: (7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-yl)methanol
InChIKey: STRYRBVTKIKRID-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3S)=O
Biological Activity: Thalidomide-SH is an E3 ubiquitin ligase cereblon (CRBN) ligand that recruits cereblon protein. Thalidomide-SH is a Thalidomide (HY-14658) derivative. Thalidomide-SH can be linked to a target protein ligand via a linker to form a PROTAC, such as SIAIS056 (HY-180969)[1].
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Thalidomide-SH | Thalidomide-SH is an E3 ubiquitin ligase cereblon (CRBN) ligand that recruits cereblon protein. Thalidomide-SH is a Thalidomide (HY-14658) derivative. Thalidomide-SH can be linked to a target protein ligand via a linker to form a PROTAC, such as SIAIS056 (HY-180969). | |||||||||||||||||||||
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