2378780-25-5
2378780-25-5
Chemical Structure
Nur77 antagonist 1
- CAS No.: 2378780-25-5
- Formula:C25H32N8OS
- Molecular Weight:492.64
InChIKey: HBLFYECMSPRSTI-UHFFFAOYSA-N
SMILES: CCN(CC)CCCNC(C1=CC2=C(N1)C=CC(NC3=NC=CC(C4=C(N=C(S4)NC)C)=N3)=C2)=O
Biological Activity: Nur77 antagonist 1(Compound ja) is a selective Nur77 antagonist(KDSPRNur77 = 91 nM). Nur77 antagonist 1 induces cancer cell apoptosis. ja displays excellent antitumor against triple-negative breast cancer (TNBC) cells[1].
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Nur77 antagonist 1 | Nur77 antagonist 1(Compound ja) is a selective Nur77 antagonist(KDSPRNur77 = 91 nM). Nur77 antagonist 1 induces cancer cell apoptosis. ja displays excellent antitumor against triple-negative breast cancer (TNBC) cells. | |||||||||||||||||||||
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