2381196-79-6
2381196-79-6
Chemical Structure
PEG3-C4-OBn
- CAS No.: 2381196-79-6
- Formula:C17H28O4
- Molecular Weight:296.40
IUPAC Name: 2-(2-((6-(benzyloxy)hexyl)oxy)ethoxy)ethan-1-ol
InChIKey: BVCUBCXUEWSFBX-UHFFFAOYSA-N
SMILES: OCCOCCOCCCCCCOCC1=CC=CC=C1
Biological Activity: PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 (HY-125878). PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PEG3-C4-OBn | 99.29% | PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 (HY-125878). PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC. | ||||||||||||||||||||
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References
- [1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5. [Content Brief]
- [2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034. [Content Brief]
