2382769-46-0
Chemical Structure
RMC-6272
Synonym(s): RM-006
- CAS No.: 2382769-46-0
- Formula:C95H141FN6O27S
- Molecular Weight:1850.22
InChIKey: SBCMKKFTXRBACH-URWOFZDBSA-N
SMILES: O=C(C1=C(C(F)=C(C=C1)S(CCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(O[C@H]2[C@@H](C[C@@H](CC2)C[C@H]([C@@]3([H])OC([C@@]4([H])N(CCCC4)C(C([C@@]5(O[C@](CC[C@H]5C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@@H]([C@@H](/C(C)=C/[C@H]([C@@H](C3)O)C)O)OC)=O)C)C)OC)O)=O)=O)=O)C)OC)=O)=O)(=O)=O)C)N6CC7=CC(C8=CN=C(N)C=C8)=CC=C7OCC6
Biological Activity: RMC-6272 (RM-006) is a bi-steric mTORC1-selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RMC-6272 | 95.05% | RMC-6272 (RM-006) is a bi-steric mTORC1-selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors. | ||||||||||||||||||||
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