2387417-06-1
2387417-06-1
Chemical Structure
Sudubrilimab
Synonym(s): HS636
- CAS No.: 2387417-06-1
- Formula:N/A
- Molecular Weight:(144.3 kDa)
IUPAC Name: 2-(4-bromo-5-fluoro-2-methoxyphenyl)acetonitrile
SMILES: [Sudubrilimab]
Biological Activity: Sudubrilimab (HS636) is an Ig G1-kappa monoclonal antibody against PDL1. Sudubrilimab is fused at the C terminus of the heavy chain to a TGF-β1 receptor Ⅱ ectodomain (TGFBR2-ECD), and which can sequester the PD-1/PD-L1 pathway and TGF-β bioactivity in the immunosuppressive tumor microenvironment[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sudubrilimab | ≥99.0% | Sudubrilimab (HS636) is an Ig G1-kappa monoclonal antibody against PDL1. Sudubrilimab is fused at the C terminus of the heavy chain to a TGF-β1 receptor Ⅱ ectodomain (TGFBR2-ECD), and which can sequester the PD-1/PD-L1 pathway and TGF-β bioactivity in the immunosuppressive tumor microenvironment. | ||||||||||||||||||||
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