2387505-78-2
Chemical Structure
Calhex 231 hydrochloride
- CAS No.: 2387505-78-2
- Formula:C25H28Cl2N2O
- Molecular Weight:443.41
IUPAC Name: 4-chloro-N-((1S,2S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)cyclohexyl)benzamide hydrochloride
InChIKey: KZPHZSFSFANQIS-GRFVZBLOSA-N
SMILES: O=C(N[C@@H]1[C@@H](N[C@@H](C2=C3C=CC=CC3=CC=C2)C)CCCC1)C4=CC=C(Cl)C=C4.[H]Cl
Biological Activity: Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca2+-sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM)[1].
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Calhex 231 hydrochloride | 99.36% | Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca2+-sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM). | ||||||||||||||||||||
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Calhex 231 hydrochloride (Standard) | ≥98% | Calhex 231 hydrochloride (Standard) is the analytical standard of Calhex 231 hydrochloride (HY-103320A). This product is intended for research and analytical applications. Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca2+-sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM). | ||||||||||||||||||||
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