240137-51-3
240137-51-3
Chemical Structure
Im-m7GDP sodium
- CAS No.: 240137-51-3
- Formula:C14H18N7NaO10P2
- Molecular Weight:529.27
InChIKey: QZTXQDIYQMOFGU-AZUPYXJKSA-M
SMILES: O=C1C([N+](C)=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP([O-])(OP(N4C=CN=C4)(O[Na])=O)=O)O3)=C2NC(N)=N1
Biological Activity: Im-m7GDP sodium is a capping reagent and also the P-imidazolide of N7-methylguanosine 5'-diphosphate. Im-m7GDP sodium introduces an m7G cap structure to the monophosphate group of branched oligoribonucleotides, and is used in nucleic acid synthesis-related research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Im-m7GDP sodium | 89.15% | Im-m7GDP sodium is a capping reagent and also the P-imidazolide of N7-methylguanosine 5'-diphosphate. Im-m7GDP sodium introduces an m7G cap structure to the monophosphate group of branched oligoribonucleotides, and is used in nucleic acid synthesis-related research. | ||||||||||||||||||||
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References
- [1]. Geng J, et al. Cap-related modifications of RNA regulate binding to IFIT proteins. RNA (New York, N.Y.). 2024 Sep 16;30(10):1292-1305. [Content Brief]
- [2]. Fukuchi K, et al. Internal cap-initiated translation for efficient protein production from circular mRNA. Nature biotechnology. 2026 Jan;44(1):120-132. [Content Brief]
- [3]. Ohashi S, et al. Selection of Short 5'-UTR of Chemically Synthesized mRNA to Improve Translation Efficiency. Chemical & pharmaceutical bulletin. 2025;73(5):449-456. [Content Brief]
