2402772-30-7
2402772-30-7
Chemical Structure
ATX inhibitor 18
- CAS No.: 2402772-30-7
- Formula:C21H17Cl2FN6O
- Molecular Weight:459.30
IUPAC Name: 4-(5-amino-3-(3-(4-methoxyphenyl)ureido)-1H-1,2,4-triazol-1-yl)benzenesulfonamide
InChIKey: ARXKMGRNHJWHRP-YPXUMCKCSA-N
SMILES: O=C(N1CCC2=C(C(NC3=CC=C(C(Cl)=C3)F)=NC=N2)C1)N/N=C/C4=CC=C(C=C4)Cl
Biological Activity: ATX inhibitor 18 is a potent ATX inhibitor with an IC50 value of 24.2 nM. ATX inhibitor 18 shows antiproliferative activity and anti-fibrosis activity. ATX inhibitor 18 suppresses collagen deposition in TGF-β-mediated cardiac fibrosis[1].
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ATX inhibitor 18 | ATX inhibitor 18 is a potent ATX inhibitor with an IC50 value of 24.2 nM. ATX inhibitor 18 shows antiproliferative activity and anti-fibrosis activity. ATX inhibitor 18 suppresses collagen deposition in TGF-β-mediated cardiac fibrosis. | |||||||||||||||||||||
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