2406276-78-4
2406276-78-4
Chemical Structure
OM-1700
- CAS No.: 2406276-78-4
- Formula:C25H23FN6O2
- Molecular Weight:458.49
IUPAC Name: N-((1S,3r)-3-(5-(5-ethoxypyridin-2-yl)-4-((S)-2-fluorophenyl)-4H-1,2,4-triazol-3-yl)cyclobutyl)picolinamide
InChIKey: ZBRBBDJXHBEGHX-QAQDUYKDSA-N
SMILES: FC1=[C@](C=CC=C1)[N@]2C([C@]3([H])C[C@H](C3)NC(C4=CC=CC=N4)=O)=NN=C2C5=CC=C(C=N5)OCC
Biological Activity: OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1].
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OM-1700 | OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM). | |||||||||||||||||||||
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