2407457-36-5
Chemical Structure
WDR5-IN-4
- CAS No.: 2407457-36-5
- Formula:C25H22Cl2FN5O
- Molecular Weight:498.38
IUPAC Name: N-(3,4-dichlorobenzyl)-3-(6-fluoro-2-methylpyridin-3-yl)-5-((2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)methyl)benzamide
InChIKey: ZPVQIJIWGMKMQN-UHFFFAOYSA-N
SMILES: ClC1=CC=C(CNC(C2=CC(CN3C(N(C)C=C3)=N)=CC(C4=C(C)N=C(F)C=C4)=C2)=O)C=C1Cl
Biological Activity: WDR5-IN-4 (Compound C6) is a WIN site inhibitor of chromatin-associated WD repeat domain 5 protein (WDR5), Kd The value is 0.1 nM. WDR5-IN-4 is able to displace WDR5 from chromatin and reduce the expression of related genes, causing translation inhibition and nucleolar stress. Has anti-cancer effects [1][1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WDR5-IN-4 | 98.13% | WDR5-IN-4 (Compound C6) is a WIN site inhibitor of chromatin-associated WD repeat domain 5 protein (WDR5), Kd The value is 0.1 nM. WDR5-IN-4 is able to displace WDR5 from chromatin and reduce the expression of related genes, causing translation inhibition and nucleolar stress. Has anti-cancer effects . | ||||||||||||||||||||
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