2409685-41-0
2409685-41-0
Chemical Structure
Anti-NASH agent 1
- CAS No.: 2409685-41-0
- Formula:C26H33NO4
- Molecular Weight:423.54
InChIKey: JMNQFYWMYKSSSA-NTEUORMPSA-N
SMILES: CC(C)(OC1=C(C)C=C(/C=C/C(C2=CC=C(NC)C=C2)=O)C=C1C)C(OC(C)(C)C)=O
Biological Activity: Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor (HY-16737)，is a potent agonist of PPAR-α/δ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Anti-NASH agent 1 | 99.23% | Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor (HY-16737)，is a potent agonist of PPAR-α/δ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect. | ||||||||||||||||||||
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