2409793-28-6
Chemical Structure
PROTAC EGFR degrader 6
- CAS No.: 2409793-28-6
- Formula:C49H57FN12O5
- Molecular Weight:913.05
IUPAC Name: (R)-N-(1-(3-(1H-pyrrolo[2,3-c]pyridin-1-yl)propanoyl)piperidin-4-yl)-2-amino-2-phenylacetamide
InChIKey: ZWLPWTDAYPOQGR-UHFFFAOYSA-N
SMILES: O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC=C3NC(CCCCCCCN4CCN(CC4)C5=CC=C(N=C5)NC6=NC=C7N=C(N=C(C7=C6)N8CCC(CC8)CO)NC9=CC=C(C=C9)F)=O
Biological Activity: PROTAC EGFR degrader 6 is a PROTAC-based degrader and inducer targeting EGFRdel19. PROTAC EGFR degrader 6 induces the degradation of EGFRdel19 via the ubiquitin-proteasome system. PROTAC EGFR degrader 6 induces apoptosis. PROTAC EGFR degrader 6 arrests cells at the G1 phase. PROTAC EGFR degrader 6 can be used in research related to non-small cell lung cancer[1].
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PROTAC EGFR degrader 6 | PROTAC EGFR degrader 6 is a PROTAC-based degrader and inducer targeting EGFRdel19. PROTAC EGFR degrader 6 induces the degradation of EGFRdel19 via the ubiquitin-proteasome system. PROTAC EGFR degrader 6 induces apoptosis. PROTAC EGFR degrader 6 arrests cells at the G1 phase. PROTAC EGFR degrader 6 can be used in research related to non-small cell lung cancer. | |||||||||||||||||||||
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