2409926-02-7
2409926-02-7
Chemical Structure
Antimycobacterial agent-1
- CAS No.: 2409926-02-7
- Formula:C18H12N4O5S
- Molecular Weight:396.38
IUPAC Name: 3-((E)-(2-isonicotinoylhydrazono)methyl)phenyl (E)-2-(2,4-dioxothiazolidin-5-ylidene)acetate
InChIKey: QCIOGWVCZFZJFV-GYGISDOKSA-N
SMILES: O=C(C1=CC=NC=C1)N/N=C/C2=CC=CC(OC(/C=C(SC(N3)=O)\C3=O)=O)=C2
Biological Activity: Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml)[1].
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Antimycobacterial agent-1 | Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml). | |||||||||||||||||||||
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