2409964-40-3
2409964-40-3
Chemical Structure
PXS-4787 hydrochloride
- CAS No.: 2409964-40-3
- Formula:C10H13ClFNO2S
- Molecular Weight:265.73
SMILES: NC/C=C(CS(=O)(C1=CC=CC=C1)=O)\F.Cl
Biological Activity: PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PXS-4787 hydrochloride | 99.71% | PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts. | ||||||||||||||||||||
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