2410327-94-3
Chemical Structure
6'-GNTI dihydrochloride
- CAS No.: 2410327-94-3
- Formula:C27H31Cl2N5O3
- Molecular Weight:544.47
IUPAC Name: 1-((4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-1,8a-dihydroxy-5,6,7,8,8a,9,14,14b-octahydro-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazol-12-yl)guanidine dihydrochloride
InChIKey: OCMMBKYOHYNDPT-AWCPWCJTSA-N
SMILES: O[C@]12[C@](C3=C(C=C4)C[C@H]2N5CC6CC6)(CC5)[C@](OC3=C4O)([H])C(NC7=CC(NC(N)=N)=CC=C87)=C8C1.Cl.Cl
Biological Activity: 6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons[1].
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6'-GNTI dihydrochloride | 6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons. | |||||||||||||||||||||
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