241139-69-5
241139-69-5
Chemical Structure
PFM067-N-morpholine
- CAS No.: 241139-69-5
- Formula:C28H45NO3
- Molecular Weight:443.66
InChIKey: OXRHDIXSNOWVQD-JDTILAPWSA-N
SMILES: C[C@H](CCC(N1CCOCC1)=O)[C@@]2([H])CC[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]23C
Biological Activity: PFM067-N-morpholine is an OSBP inhibitor that binds to the ORD domain of the host lipid transfer protein, which is involved in HSV-2 replication. PFM067-N-morpholine has a Kd of 4.93 μM for human OSBP. PFM067-N-morpholine inhibits HSV-2 replication with a selectivity index, with an EC50 of 8 nM in Hela cells. PFM067-N-morpholine can be used for research on HSV-2 infection[1].
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PFM067-N-morpholine | PFM067-N-morpholine is an OSBP inhibitor that binds to the ORD domain of the host lipid transfer protein, which is involved in HSV-2 replication. PFM067-N-morpholine has a Kd of 4.93 μM for human OSBP. PFM067-N-morpholine inhibits HSV-2 replication with a selectivity index, with an EC50 of 8 nM in Hela cells. PFM067-N-morpholine can be used for research on HSV-2 infection. | |||||||||||||||||||||
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