2411407-25-3
2411407-25-3
Chemical Structure
Modzatinib
Synonym(s): ITK kinase-IN-1
- CAS No.: 2411407-25-3
- Formula:C18H21F2N5O
- Molecular Weight:361.39
InChIKey: KULMFWJHZABAFA-DMDPSCGWSA-N
SMILES: FC(F)(C1)[C@H]1C2=CNC3=NC=NC(N[C@H]4CN([C@H](CC4)C)C(C=C)=O)=C23
Biological Activity: Modzatinib (ITK kinase-IN-1) is an oral active, selective, covalent ITK/JAK3 dual-target inhibitor with IC50 values of 8 nM and 23 nM, respectively. Modzatinib exhibits anti-inflammatory activity and can be used in the research of autoimmune and inflammatory diseases[1].
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Modzatinib | Modzatinib (ITK kinase-IN-1) is an oral active, selective, covalent ITK/JAK3 dual-target inhibitor with IC50 values of 8 nM and 23 nM, respectively. Modzatinib exhibits anti-inflammatory activity and can be used in the research of autoimmune and inflammatory diseases. | |||||||||||||||||||||
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