2411845-57-1
Chemical Structure
BODIPY-FL staurosporine
- CAS No.: 2411845-57-1
- Formula:C49H54BF2N7O7
- Molecular Weight:901.80
SMILES: C[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C[C@H]([C@H]2OC)NCCOCCOCCOCCNC(CCC8=CC=C(C=C9C(C)=C%10)[N-]8[B+3]([F-])([F-])[N]9=C%10C)=O)([H])O1)C%11=CC=CC=C7%11
Biological Activity: BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery[1].
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BODIPY-FL staurosporine | 95.4% | BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery. | ||||||||||||||||||||
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