2412004-88-5
2412004-88-5
Chemical Structure
Livmoniplimab
Synonym(s): ABBV-151; ARGX-115
- CAS No.: 2412004-88-5
- Formula:N/A
- Molecular Weight:(146.22 kDa)
SMILES: [Livmoniplimab]
Biological Activity: Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Livmoniplimab | 99.25% | Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors. | ||||||||||||||||||||
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References
- [1]. Tindall RR, et al. The TGF-β superfamily as potential therapeutic targets in pancreatic cancer. Front Oncol. 2024 Mar 4;14:1362247. [Content Brief]
- [2]. Guo J, et al. A novel GARP humanized mouse model for efficacy assessment of GARP-targeting therapies. Int Immunopharmacol. 2024 Mar 30;130:111782. [Content Brief]
