2412854-49-8
2412854-49-8
Chemical Structure
Lavengratinib
Synonym(s): ABSK061
- CAS No.: 2412854-49-8
- Formula:C26H27Cl2N5O4
- Molecular Weight:544.43
InChIKey: SQMXIBXIVSOOII-UHFFFAOYSA-N
SMILES: O=C1C(C2=C(C(OC)=CC(OC)=C2Cl)Cl)=CC3=CN=C(C4=CN(CCN5CCOCC5)N=C4)C=C3N1C
Biological Activity: Lavengratinib (ABSK061) is a FGFR2/FGFR3 inhibitor. Lavengratinib selectively inhibits FGFR2 and FGFR3 signaling pathways and reduces the risk of FGFR1-mediated hyperphosphatemia. Lavengratinib is suitable for research on advanced solid tumors (including cholangiocarcinoma, gastric cancer, non-small cell lung cancer, cervical cancer and urothelial cancer)[1].
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Lavengratinib | Lavengratinib (ABSK061) is a FGFR2/FGFR3 inhibitor. Lavengratinib selectively inhibits FGFR2 and FGFR3 signaling pathways and reduces the risk of FGFR1-mediated hyperphosphatemia. Lavengratinib is suitable for research on advanced solid tumors (including cholangiocarcinoma, gastric cancer, non-small cell lung cancer, cervical cancer and urothelial cancer). | |||||||||||||||||||||
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