2412937-64-3
2412937-64-3
Chemical Structure
TLR8 agonist 2
- CAS No.: 2412937-64-3
- Formula:C16H22N8
- Molecular Weight:326.40
IUPAC Name: (R)-N4-(2-methyl-1-(4H-1,2,4-triazol-3-yl)hexan-2-yl)pyrido[3,4-d]pyrimidine-2,4-diamine
InChIKey: MFXIZGDOEUUJFM-MRXNPFEDSA-N
SMILES: CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3
Biological Activity: TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 shows less active against human TLR7 (EC50 of 33.33 μM)[1].
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TLR8 agonist 2 | TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 shows less active against human TLR7 (EC50 of 33.33 μM). | |||||||||||||||||||||
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