2413565-15-6
2413565-15-6
Chemical Structure
COX-2/15-LOX-IN-1
- CAS No.: 2413565-15-6
- Formula:C21H21N7S3
- Molecular Weight:467.63
IUPAC Name: (E)-2-(1-((4-(2-(methylthio)-1H-benzo[d]imidazol-1-yl)thiazol-2-yl)amino)propan-2-ylidene)-N-phenylhydrazine-1-carbothioamide
InChIKey: ZZPGKCHSCRXXCO-VULFUBBASA-N
SMILES: S=C(NC1=CC=CC=C1)N/N=C(C)/CNC2=NC(N3C(SC)=NC4=CC=CC=C34)=CS2
Biological Activity: COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase enzyme (15-LOX) inhibitor with IC50 values of 10.65, 0.075 and 2.98 μM against COX-1, COX-2 and 15-LOX, respectively. COX-2/15-LOX-IN-1 shows anti-inflammatory activity[1].
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COX-2/15-LOX-IN-1 | COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase enzyme (15-LOX) inhibitor with IC50 values of 10.65, 0.075 and 2.98 μM against COX-1, COX-2 and 15-LOX, respectively. COX-2/15-LOX-IN-1 shows anti-inflammatory activity. | |||||||||||||||||||||
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