2413733-33-0
2413733-33-0
Chemical Structure
MG degrader 2
- CAS No.: 2413733-33-0
- Formula:C26H27N3O5
- Molecular Weight:461.51
InChIKey: RLTDCECVFNMASN-UHFFFAOYSA-N
SMILES: O=C(C(N(CC1=C2C=CC=C1OCCCC(N3CCCC4=C3C=CC=C4)=O)C2=O)CC5)NC5=O
Biological Activity: MG degrader 2 (Compound CM-2) is a CRBN-dependent molecular glue degrader. MG degrader 2 induces ZFP91, FIZ1 and PI4KB degradation. MG degrader 2 has anti-proliferative activity against MM.1S cells (IC50 = 162 nM). MG degrader 2 can be used for the research of cancer, such as multiple myeloma[1].
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MG degrader 2 | MG degrader 2 (Compound CM-2) is a CRBN-dependent molecular glue degrader. MG degrader 2 induces ZFP91, FIZ1 and PI4KB degradation. MG degrader 2 has anti-proliferative activity against MM.1S cells (IC50 = 162 nM). MG degrader 2 can be used for the research of cancer, such as multiple myeloma. | |||||||||||||||||||||
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