2414056-31-6
2414056-31-6
Chemical Structure
Perzebertinib
Synonym(s): ZN-A-1041
- CAS No.: 2414056-31-6
- Formula:C27H26F2N8O3
- Molecular Weight:548.54
InChIKey: PTKRHBXNNDLRPO-OAQYLSRUSA-N
SMILES: COC1=C(C2=C(N=CN=C2NC3=CC(C)=C(C=C3)OC4=CC5=NC=NN5C=N4)C=C1)O[C@@H]6CCN(CC6(F)F)C
Biological Activity: ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC50s of 9.5 nM and 12 μM respectively. ZN-A-1041 can be used for research of cancer and inflammation[1].
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Perzebertinib | ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC50s of 9.5 nM and 12 μM respectively. ZN-A-1041 can be used for research of cancer and inflammation. | |||||||||||||||||||||
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