2414276-32-5
Chemical Structure
NEP
Synonym(s): VDP-green (NEP)
- CAS No.: 2414276-32-5
- Formula:C29H31AsN4O5S2
- Molecular Weight:654.63
IUPAC Name: (2-(4-(3-aminopropanamido)phenyl)-1,3,2-dithiarsolan-4-yl)methyl (2-butyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl)carbamate
InChIKey: GNUHSLLRVGIPIB-UHFFFAOYSA-N
SMILES: O=C(N1CCCC)C2=C3C(C(NC(OCC4S[As](SC4)C5=CC=C(C=C5)NC(CCN)=O)=O)=CC=C3C1=O)=CC=C2
Biological Activity: NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm). NEP has the potential for parkinsonism[1].
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NEP | NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm). NEP has the potential for parkinsonism. | |||||||||||||||||||||
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