2414594-29-7
Chemical Structure
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin
- CAS No.: 2414594-29-7
- Formula:C44H51FN8O12
- Molecular Weight:902.92
IUPAC Name: 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((9S,12S,15S)-1-((S)-4-ethyl-8-fluoro-4-hydroxy-9-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-11-yl)-9,12-dimethyl-3,8,11,14-tetraoxo-5-oxa-2,7,10,13-tetraazahexadecan-15-yl)hexanamide
InChIKey: BENZIHFYRZCGIE-NJUCZJDQSA-N
SMILES: O=C(C=CC1=O)N1CCCCCC(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(NCOCC(NCC2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C=C62)=O)=O)=O)=O)=O
Biological Activity: MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin | 96.17% | MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC). | ||||||||||||||||||||
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