2414598-85-7
2414598-85-7
Chemical Structure
hCAIX-IN-12
- CAS No.: 2414598-85-7
- Formula:C18H14N4O3S2
- Molecular Weight:398.46
IUPAC Name: 4-amino-N-(2-(3-phenyl-1,2,4-oxadiazol-5-yl)thiophen-3-yl)benzenesulfonamide
InChIKey: BKPTXQBGBXVYFW-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(N)C=C1)(NC2=C(C3=NC(C4=CC=CC=C4)=NO3)SC=C2)=O
Biological Activity: hCAIX-IN-12 is a potent hCAIX inhibitor with IC50 values of 0.74, 10.78 μM for CAIX and CAII, respectively. hCAIX-IN-12 shows antiproliferative effect and induces apoptosis. hCAIX-IN-12 increases ROS production. hCAIX-IN-12 has the potential for the research of colorectal cancer (CRC) [1].
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hCAIX-IN-12 | hCAIX-IN-12 is a potent hCAIX inhibitor with IC50 values of 0.74, 10.78 μM for CAIX and CAII, respectively. hCAIX-IN-12 shows antiproliferative effect and induces apoptosis. hCAIX-IN-12 increases ROS production. hCAIX-IN-12 has the potential for the research of colorectal cancer (CRC) . | |||||||||||||||||||||
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