2415018-86-7
Chemical Structure
RSV-IN-5
- CAS No.: 2415018-86-7
- Formula:C28H37N7O2
- Molecular Weight:503.64
IUPAC Name: (22S,E)-15-((S)-3-aminopyrrolidin-1-yl)-45,10-dimethyl-5-oxa-10-aza-1(2,7)-pyrazolo[1,5-a]pyrimidina-2(2,1)-piperidina-4(1,2)-benzenacyclodecaphan-3-one
InChIKey: RNKULGCYSCGYOZ-REWPJTCUSA-N
SMILES: CN1C2=CC(N3CC[C@@H](C3)N)=NC4=CC([C@@]5([H])N(CCCC5)C(C6=CC(C)=CC=C6OCCCC1)=O)=NN24
Biological Activity: RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM)[1].
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RSV-IN-5 | RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM). | |||||||||||||||||||||
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