2415933-42-3
2415933-42-3
Chemical Structure
Casirivimab
Synonym(s): REGN10933
- CAS No.: 2415933-42-3
- Formula:N/A
- Molecular Weight:(145.24 kDa)
IUPAC Name: tert-butyl (4-(2-fluorophenyl)piperidin-4-yl)carbamate
SMILES: [Casirivimab]
Biological Activity: Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab (HY-P99342), which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Casirivimab | 99.54% | Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab (HY-P99342), which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms. | ||||||||||||||||||||
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References
- [1]. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. Casirivimab. 2022 May 15. [Content Brief]
- [2]. Lee Tatham, et al. Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiol Spectr. 2024 Aug 6;12(8):e0391623. [Content Brief]
