2416338-55-9
2416338-55-9
Chemical Structure
Microtubule inhibitor 5
- CAS No.: 2416338-55-9
- Formula:C22H15FN2O4
- Molecular Weight:390.36
IUPAC Name: (Z)-3-((Z)-3-(4-fluorophenoxy)benzylidene)-6-(furan-2-ylmethylene)piperazine-2,5-dione
InChIKey: HVDIOKFBMGISBM-YXZJEIOKSA-N
SMILES: O=C1N/C(C(N/C1=C\C2=CC(OC3=CC=C(C=C3)F)=CC=C2)=O)=C\C4=CC=CO4
Biological Activity: Microtubule inhibitor 5 (compound 17f) is a potent microtubule inhibitor. Microtubule inhibitor 5 shows cytotoxicity with an IC50 value of 154.5 nM for NCI-H460 cells. Microtubule inhibitor 5 shows good cell permeability[1].
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Microtubule inhibitor 5 | Microtubule inhibitor 5 (compound 17f) is a potent microtubule inhibitor. Microtubule inhibitor 5 shows cytotoxicity with an IC50 value of 154.5 nM for NCI-H460 cells. Microtubule inhibitor 5 shows good cell permeability. | |||||||||||||||||||||
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