2416338-64-0
2416338-64-0
Chemical Structure
Microtubule inhibitor 6
- CAS No.: 2416338-64-0
- Formula:C24H19FN2O5
- Molecular Weight:434.42
IUPAC Name: (Z)-3-((Z)-3-(4-fluorophenoxy)benzylidene)-6-((5-(methoxymethyl)furan-2-yl)methylene)piperazine-2,5-dione
InChIKey: ZLGSUDHLMJERRN-HDSGJDLKSA-N
SMILES: COCC1=CC=C(O1)/C=C2NC(/C(NC\2=O)=C/C3=CC(OC4=CC=C(C=C4)F)=CC=C3)=O
Biological Activity: Microtubule inhibitor 6 (compound 17o) is a potent microtubule inhibitor. Microtubule inhibitor 6 shows cytotoxicity with IC50s of 14.0, 6.6, 7.0 nM for NCI-H460, BxPC-3, HT-29 cells, respectively. Microtubule inhibitor 6 efficiently inhibits microtubule polymerization[1].
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Microtubule inhibitor 6 | Microtubule inhibitor 6 (compound 17o) is a potent microtubule inhibitor. Microtubule inhibitor 6 shows cytotoxicity with IC50s of 14.0, 6.6, 7.0 nM for NCI-H460, BxPC-3, HT-29 cells, respectively. Microtubule inhibitor 6 efficiently inhibits microtubule polymerization. | |||||||||||||||||||||
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