2416338-65-1
2416338-65-1
Chemical Structure
Microtubule inhibitor 7
- CAS No.: 2416338-65-1
- Formula:C25H19FN2O5
- Molecular Weight:446.43
IUPAC Name: (Z)-3-((Z)-3-(4-fluorobenzoyl)benzylidene)-6-((5-(methoxymethyl)furan-2-yl)methylene)piperazine-2,5-dione
InChIKey: XOIXHBHDGPMJTM-HDSGJDLKSA-N
SMILES: O=C(C1=CC=CC(/C=C2NC(/C(NC\2=O)=C/C3=CC=C(O3)COC)=O)=C1)C4=CC=C(C=C4)F
Biological Activity: Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
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Microtubule inhibitor 7 | Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level. | |||||||||||||||||||||
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