2418022-85-0
2418022-85-0
Chemical Structure
TMX-2164
- CAS No.: 2418022-85-0
- Formula:C25H24ClFN6O6S
- Molecular Weight:591.01
IUPAC Name: 3-(((5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)amino)methyl)benzenesulfonyl fluoride
InChIKey: VNVCMPVIJOIVJD-UHFFFAOYSA-N
SMILES: O=C(COC1=CC2=C(N(C)C1=O)C(OC)=CC(NC3=NC(NCC4=CC=CC(S(=O)(F)=O)=C4)=NC=C3Cl)=C2)NC
Biological Activity: TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells[1].
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TMX-2164 | TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells. | |||||||||||||||||||||
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