2418576-06-2
Chemical Structure
mEH-IN-1
- CAS No.: 2418576-06-2
- Formula:C16H17F6NOS
- Molecular Weight:385.37
IUPAC Name: 2-((3,5-bis(trifluoromethyl)benzyl)thio)-2-cyclopentylacetamide
InChIKey: HFFWMFZWOVDMTI-UHFFFAOYSA-N
SMILES: NC(C(C1CCCC1)SCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O
Biological Activity: mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].
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mEH-IN-1 | 99.96% | mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer. | ||||||||||||||||||||
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