2418594-00-8
2418594-00-8
Chemical Structure
(1R,2R)-ML-SI3
Synonym(s): (-)-trans-ML-SI3
- CAS No.: 2418594-00-8
- Formula:C23H31N3O3S
- Molecular Weight:429.58
IUPAC Name: N-((1R,2R)-2-(4-(2-methoxyphenyl)piperazin-1-yl)cyclohexyl)benzenesulfonamide
InChIKey: OVTXOMMQHRIKGL-NHCUHLMSSA-N
SMILES: COC1=CC=CC=C1N2CCN([C@@H]3CCCC[C@H]3NS(C4=CC=CC=C4)(=O)=O)CC2
Biological Activity: (1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of three isoforms of TRPML. (1R,2R)-ML-SI3 inhibits TRPMLs with IC50s of 1.6 μM (TRPML1), 2.3 μM (TRPML2), and 12.5 μM (TRPML3), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(1R,2R)-ML-SI3 | 99.79% | (1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of three isoforms of TRPML. (1R,2R)-ML-SI3 inhibits TRPMLs with IC50s of 1.6 μM (TRPML1), 2.3 μM (TRPML2), and 12.5 μM (TRPML3), respectively. | ||||||||||||||||||||
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